Venlafaxine and SSRI remission data revisited
نویسندگان
چکیده
منابع مشابه
Higher serum DHEA concentrations before and after SSRI treatment are associated with remission of major depression.
BACKGROUND Dehydroepiandrosterone (DHEA) and its sulfated ester DHEA-sulfate (DHEA-S), (together DHEA[S]), are the most abundant adrenal steroids in humans and are found in blood and the brain, where they function as neurosteroids with direct receptor affinities. Preclinical studies suggest that DHEA(S) has antidepressant/neuroprotective properties, and exogenously administered DHEA has shown a...
متن کاملSwitching to another SSRI or to venlafaxine with or without cognitive behavioral therapy for adolescents with SSRI-resistant depression: the TORDIA randomized controlled trial.
CONTEXT Only about 60% of adolescents with depression will show an adequate clinical response to an initial treatment trial with a selective serotonin reuptake inhibitor (SSRI). There are no data to guide clinicians on subsequent treatment strategy. OBJECTIVE To evaluate the relative efficacy of 4 treatment strategies in adolescents who continued to have depression despite adequate initial tr...
متن کاملPharmacy and medical costs associated with switching between venlafaxine and SSRI antidepressant therapy for the treatment of major depressive disorder.
BACKGROUND While much has been published on utilization of antidepressants and associated resource use, surprisingly little information is available on the relationship between a change in antidepressant agent and health care utilization. Given that many patients will not respond to initial therapy (and therefore would be candidates for switching treatment) and the array of antidepressant medic...
متن کاملVenlafaxine had higher response and remission rates than paroxetine in non-chronic treatment resistant depression
Patients 123 patients (mean age 43 y, 72% women) with major depression (DSM-III-R) of < 8 months duration. Inclusion criteria were age 18–60 years, 17-item Hamilton Depression Rating Scale (HDRS) score >18 and resistance (Clinical Global Impression [CGI] scale improvement score of 3 at the second treatment) to 2 antidepressant treatments for the current depression (therapeutic dose for >4 wk, t...
متن کاملVenlafaxine had higher response and remission rates than paroxetine in non-chronic treatment resistant depression
Patients 123 patients (mean age 43 y, 72% women) with major depression (DSM-III-R) of < 8 months duration. Inclusion criteria were age 18–60 years, 17-item Hamilton Depression Rating Scale (HDRS) score >18 and resistance (Clinical Global Impression [CGI] scale improvement score of 3 at the second treatment) to 2 antidepressant treatments for the current depression (therapeutic dose for >4 wk, t...
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ژورنال
عنوان ژورنال: The British Journal of Psychiatry
سال: 2004
ISSN: 0007-1250
DOI: 10.1192/bjp.184.5.452-a